产品货号：
Z30038
中文名称：
CYP19A1抗体
英文名称：
Anti-CYP19A1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CYP19A1 Antibody |
| 指标别名 | Aromatase;CYPXIX;Cytochrome P-450AROM;Cytochrome P450 19A1;Estrogen synthase;CYP19A1;ARO1;CYAR;CYP19 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | CYP19A1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Aromatase(485-503aa KNMLEMIFTPRNSDRCLEH). |
| 实际分子量 | 58KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Aromatase is an enzyme responsible for a key step in the biosynthesis of estrogens.It is a member of the cytochrome P450 superfamily,which are monooxygenases that catalyze many reactions involved in steroidogenesis.In particular,aromatase is responsible for the aromatization of androgens into estrogens.The CYP19 gene spans at least 70kb of genomic DNA and contains 10 exons.By in situ hybridization,the ARO gene is mapped to 15q21.1.The aromatase enzyme can be found in many tissues including gonads,brain,adipose tissue,placenta,blood vessels,skin,bone,and endometrium,as well as in tissue of endometriosis,uterine fibroids,breast cancer,and endometrial cancer.It is an important factor in sexual development.Some bodybuilders taking steroids also take antiaromatase supplements to prevent excess testosterone conversion into estrogens,which can cause gynecomastia. |
| Uniprot ID | P11511 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | cytochrome P450,family 19,subfamily A,polypeptide 1 |
| 蛋白名全称 | Aromatase |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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